Well, the witch is a metaphor for the Mark and/or John (it’s hard to tell anymore), and because Hansel had to “eat Gretl’s heart” I am suddenly terrified for Sam.
That’s a (cue 10×01 opening) *Heartbreaker*
Patmore!Witch=Lucifer=John?
Hansel = Cain = Dean?
Gretel = Abel = Sam?